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  • As far as croone () is concerned, he was created a doctor of medicine in cambridge by royal mandate and was chosen one of the first fellows of the royal society in , after the grant of their charter, and he frequently sat upon the councilhis work here on muscular motion appeared in london in and then (like the work of willis) came out in amsterdam in the same yearsmall piece of one page missing, without affecting the text (see photo) the is the continental 8vo/12mo edition of willis’s work which appeared first in the same year in londonfrom this perspective, willis examined the brain and tried to relate his anatomic findings in cadavers to living functionsplease click on "respond to advert" (orange button) to get redirected to the catawiki websitethe date on the first title page has been scratched; there are some signs of wear on the calf binding (slightly later perhaps), which shows signs of having been washed rather too readily with soap, some of which has become encrusted (remediable, one imagines)the cerebellum and brainstem were correctly assessed as being more instinctual and acting reflexively, independent of the higher brain functionsthe quarto edition supplied the plates for this small octavo edition (plates are from drawings by sir christopher wren & richard lower)this is probably the first demonstration of the blood supply to the pituitary gland originating from the internal carotid arterieshe discussed the swift integration of the senses into the function of the brain and the quick reactions that lead from sight to imaginationhe also discussed reflex stress reactions to fever and the quickening of the pulse and respirationcatawiki’s goal is to make special objects universally availablehe described the ophthalmic artery as bringing blood to the ocular region and attributed sleepiness after the consumption of alcoholic beverages to distension or “boiling up” around the eyestwo texts in one smallish octavo volume (134 x 76 mm): [11ff/f], 32 page [14] with 16 plates in the first text (15 folding) and two plates in the second textnote too that an 8vo/12mo appeared in in london: it is not clear whether the amsterdam edition here predates thisturning to the work of willis, the book ushered in the era of modern neuroanatomy and laid the groundwork for future neuroanatomic and neurophysiological investigationsat one point, he injected black ink into the carotid arteries and noted that the exterior part of the pituitary gland was stained blackthroughout his book, willis attempted to assign functions to various anatomic componentsit is quite likely the first issue of the book following the first edition quartoour weekly auctions feature thousands of unusual, rare, and exceptional objects you won’t find in just any storewillis attributed pulse and respiration to cerebellar functionthe company of surgeons appointed him in their anatomy lecturer on the muscles, in succession to sir charles scarborough, and he held that office till his deathin superb conditionmost remarkable about this study (which first proposes the term neurology, in greek, ?e???????a) is the attempt of the author, thomas willis () to define areas of localisation of brain function and to discuss the anatomic features of the brain from a dynamic and functional perspectivethis quarto edition is listed as having 15 plates, not 16 as here (see listing at bonhams in ) it should also be noted that some copies of the two books in one volume list only 15 plates, rather than 18the frontispiece appeared in the schlagen edition and is indeed datedthe only copy traced is at the wellcome library but this copy is missinghe also conducted experiments to investigate the cadaveric anatomic features of the braintruly a classic bookare you interested in this item? this item is up for auction at catawikiit must be remembered that, at that time, anatomy was the fundamental science of medicine and formed the basis for assigning function to human organshe also described the internal carotid artery at the base of the cranium and its emergence into the intradural compartmenthowever, willis was more concerned with the flow of ‘humours’, or toxic substances, from the brain through the floor of the third ventricle and into the pituitary glandthe library suggests the possibility of a frontispiece but this is not so

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